medical conditions

Paget's disease: excessive osteoclastic-mixed osteoclastic-osteoblastic activity. ? a/w paramyxovirus eleated ALP with normal Ca, Po4, aminotransferase. Elderly patient, bone scan. Abnormal bone architecture. normal PTH <1% osteosarcoma.

Treatment: bisphosphonates (risderonic, alendronic, pamidronic acids), calcitonin , vitamin D, exercise.

Osteoporosis: normal calcium, phosphate, variable ALP, PTH unaffected, decreased bone mass.

abnormal PTH: osteomalacia/rickets, osteitis fibrosa cystica

Gullain Barre: AIDP acute INFLAMMATORY demyelinating polyneuropathy. ascending paralysis, autonomic dysfunction. CSF: elevated protein (10-1000mg/dL) , no increased cell count. intubation if VC 20ml/kg NIF <-25cmH20, more than 30% decrease in either VC of NIF within 24 hours

diagnosis: nerve conduction studies

Treatment: IVIG/ plasmapheresis, supportive care.