http://www.esra-learning.com/site/generalites/anticoagulation/b_anticoagulation.htm
unfractionated heparin
during low-dose administration of unfractionated heparins, an interval of 4 hours should be observed between heparin administration (usually 5000 IU s.c.) and epidural puncture or catheter removal, in order to avoid bleeding complications. Any repeat administration of low-dose heparin should then follow at the earliest after 1 hour.
risk of haemorrhage after epidural anaesthesia and subsequent heparinization is not increased if the heparinization is carried out at the earliest 1 hour after spinal/epidural puncture and is closely monitored. (and no concurrent antiplatelets)
LMW Heparin
The advantages-high level of bioavailability (ca. 100%) after sc administration and their long half-life of 4–7 hours. Max effect 4hrs post admin
-gold standard for thromboembolism prophylaxis in high-risk patients
-no difference in clinical efficacy has yet been demonstrated between the individual preparations. low risk of HIT but should not be used in patients with HIT
Aspirin
The safety of neuraxial regional anaesthesia in patients receiving acetylsalicylic acid is mainly based on three studies [40–42]. Although the Collaborative Low-dose Aspirin Study in Pregnancy (CLASP)
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